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Evidence For HIFU Focal Therapy For Prostate Cancer

As a group of consultants we have devoted much of our working lives to the treatment of prostate cancer. We believe that focal therapy is the best form of treatment for patients with early stage prostate cancer. We also know that many patients who are good candidates for focal therapy are never made aware of this option.

We understand that you may be surprised if you didn’t know focal therapy was a treatment option and therefore sceptical about it. We urge you to get in contact with us and we will answer any questions you may have on focal therapy and whether it is the best treatment option for you. If you would rather do your own research then there are many available sources on the internet.

By far the most far reaching and evidence based study on the outcomes of focal therapy being used to treat prostate cancer is the multi-centre study of 5-year outcomes published in October 2018.

You can access the full report analysis here or download the full report herePlease read this important study in detail.

Highlights from this study include:

  • In this multi-centre study 625 prostate cancer patients were treated with focal therapy using high-intensity focused ultrasound (HIFU)

  • The cancer-specific survival rate was 100%


  • In this cohort urinary incontinence (any pad use) was 2%


  • Focal HIFU therapy for patients with clinically significant prostate cancer that has not spread has a low probability of side effects and is effective at 5 years

  • The primary endpoint, failure-free survival (FFS), was defined as freedom from radical or systemic therapy, metastases (the development of secondary malignant growths at a distance from a primary site of cancer) and cancer-specific mortality. This failure-free survival rate was 88% aligned to the cancer-specific survival rate of 100%.

  • Overall conclusion was that focal therapy for select patients with clinically significant non-metastatic prostate cancer is effective in the medium term and has a low probability of side effects

It is important to note that as the study was conducted over a 5 year period it can only include the ‘medium term’ in its conclusion as long term is defined as a 10 year span.

This study is the biggest of its kind and demonstrates why focal therapy should be a part of any treatment consideration process for early stage prostate cancer.

“HIFU is something people need to be aware of – I believe this treatment should be more widely available and more widely promoted. It wasn’t something suggested to me as a possibility by my urologist and I actually raised it myself. I would recommend HIFU and in fact have recommended it to others.”

Keith (The Focal Therapy Clinic Patient)

Get In Touch

As a group of consultants we are passionate about all prostate cancer sufferers knowing about all of their treatment options.

Based upon the details that you know and can provide to us, we will send you a Plain English personalised preliminary suitability report for HIFU Focal Therapy treatment of your prostate cancer.

You can use the information we provide in your conversations with your existing NHS and/or private treatment consultant. Should you wish to talk with us further we would be grateful to help you, but there is absolutely no obligation for you to do so whatsoever.