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HIFU Treatment for Prostate Cancer

  • NICE-approved focal therapy (IPG424) that treats prostate cancer as a day case procedure.
  • 90%+ sexual function preserved, less than 2% urinary incontinence (FTC audit, n=265).
  • Over 2,000 procedures performed across seven UK centres by GMC-registered consultant urological surgeons.
  • Most men return to work within two weeks — no surgical wound, no stitches, no radiation.
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What is HIFU? Is HIFU right for me? HIFU success rates Advantages & Disadvantages What to Expect What are the side-effects? Questions
Nice Approved
NICE Approved (IPG424)
2,000+
Focal Therapy
Procedures Performed
Nice Approved
97% Urinary Continence Rate
(FTC audit, n=265)


Same-day discharge
Most men go home the same day. 85% return to work within 2 weeks (FTC patient data)


90%+ function preserved
Over 90% of men maintain sexual function; less than 2% experience incontinence (FTC audit, n=265)


Minimally invasive
No incisions, no radiation, no hormones. Performed under general anaesthetic in 1-2 hours

HIFU (High-Intensity Focused Ultrasound) is a NICE-approved focal therapy (IPG424) that uses precisely targeted ultrasound waves to destroy cancerous tissue in the prostate while preserving surrounding healthy structures. It is performed as a day-case procedure under general anaesthetic, typically taking one to two hours, with most men going home the same evening — no overnight hospital stay required.

In our clinic's experience treating over 2,000 patients, HIFU effectively treats localised prostate cancer with 90%+ sexual function preservation and less than 2% risk of urinary incontinence (FTC audit, n=265). The Focal Therapy Clinic offers HIFU across seven UK centres, led by four GMC-registered consultant urological surgeons who assess every patient individually through detailed MRI review and multidisciplinary discussion.

Every patient case is reviewed at our weekly multidisciplinary team meeting (MDT) where your case is discussed in detail by our team of consultant urological surgeons, oncologists, and uro-radiologists. Our uro-radiology team, led by Dr Clare Allen, a prostate MRI and focal therapy pioneer, develops personalised treatment plans based on detailed review of your MRI images and biopsy results.

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Learn more about how HIFU works

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Mr. Raj Nigam: Does Focal Therapy work?
00:41
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SUMMARY
Mr. Raj Nigam (Consultant Urologist, The Focal Therapy Clinic): Focal therapy works, but not all men are suitable. Careful selection is crucial, with a detailed analysis ensuring that only the right candidates receive treatment for their specific cancer, maximizing effectiveness and safety. Mr. Raj Nigam - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-raj-nigam/ Focal Therapy - https://www.thefocaltherapyclinic.co.uk/focal-therapy/ suitability - https://www.thefocaltherapyclinic.co.uk/focal-therapy/medical-suitability/

TRANSCRIPT
Mr. Raj Nigam: ### **Does Focal Therapy Work?** Yes, **focal therapy is effective**—I wouldn’t have dedicated **18 years to this field if it didn’t work**. However, **not every man is suitable** for focal therapy. ### **How We Determine Suitability** - Many men **like the concept of focal therapy**, but careful **patient selection is critical**. - We spend significant time **analyzing existing medical data** or conducting **further assessments** to confirm whether a patient is a good candidate. - We ensure that the **treatment is tailored to the individual and their specific prostate cancer characteristics**. ### **A Highly Personalized Approach** Focal therapy is **not a one-size-fits-all treatment**—it is a **nuanced, carefully selected option** for the **right patients**. For those who qualify, **it offers excellent outcomes with minimal side effects**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: How successful is HIFU?
02:16
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Success in prostate cancer treatment isnt just about survivalit includes preserving urinary and sexual function. After 78 years, focal therapy, surgery, and radiotherapy show equivalent cancer control, but focal therapy has far fewer side effects, making it a compelling option for many men. Mr Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ HIFU - https://www.thefocaltherapyclinic.co.uk/focal-therapy/hifu-treatment-prostate-cancer/ success rates - https://www.thefocaltherapyclinic.co.uk/focal-therapy/success-and-clinical-evidence/ why choose focal therapy - https://www.thefocaltherapyclinic.co.uk/why-choose-focal-therapy/ 00:00 What Does Success Mean After Treatment? 00:02 Doctors Focus on Cancer Outcomes, But Patients Care About More 00:13 Continence & Urinary Function as Key Measures 00:16 Sexual Function as a Major Part of Success 00:21 Success Must Include All Domains, Not Just Cancer Control 00:29 How Cancer-Control Success Is Measured 00:33 Evidence from Observational Studies 00:41 What Counts as Treatment Failure (Surgery, Radiotherapy, Hormones) 00:52 Serious Outcomes Like Mortality Rare in These Timeframes 01:00 Comparing Long-Term Results Across Treatments 01:04 Retreatment Needed for ~1 in 5 Men 01:09 After 78 Years, Failure-Free Survival Is Similar Between Surgery, Radiotherapy & Focal Therapy 01:17 Why This Gives Confidence in Focal Therapy 01:23 Side Effects: Focal Therapy vs Radical Treatments 01:25 Studies Show Dramatically Fewer Side Effects With Focal Therapy 01:32 Choosing Between Radical Treatment and Focal Therapy 01:40 If Side Effects Matter More Than Certainty, Focal Therapy May Be Preferred 01:45 Other Treatments Remain Available if Retreatment Is Needed 01:52 Lower Side Effects Provide Greater Short-Term Benefit 02:04 Long-Term Options Still Exist If Needed

TRANSCRIPT
Mr. Tim Dudderidge: Success after **prostate cancer treatment** can be measured in **several ways**. While doctors tend to focus on **cancer control**, men often place equal importance on: - **Urinary function and continence**. - **Sexual function and quality of life**. ### **Cancer Control Success** The best measure of treatment success comes from **observational studies**, where we track patients over time to assess **treatment failure**. - Failure is defined as **requiring surgery, radiotherapy, or hormone therapy** after initial focal therapy. - **Less than 20% of men** need a second focal therapy treatment. - After **7–8 years of follow-up**, success rates between **focal therapy, surgery, and radiotherapy** are **equivalent** in terms of cancer control. ### **Side Effects & Quality of Life** - **Focal therapy has dramatically fewer side effects** than radical treatments. - For men choosing between **radical treatment or focal therapy**, the **trade-off** is: - **Focal therapy** → Lower side effects, but a small chance of needing another treatment later. - **Surgery/Radiotherapy** → Higher certainty, but with **greater impact on continence and sexual function**. For men prioritizing **quality of life**, focal therapy provides **significant benefits in the short term**, and if needed, **other treatment options remain available** in the future.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Raj Nigam: Is NanoKnife better than HIFU?
01:00
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SUMMARY
Mr. Raj Nigam (Consultant Urologist, The Focal Therapy Clinic): HIFU and NanoKnife are chosen based on tumor location. HIFU treats the posterior prostate, while NanoKnife targets anterior tumors. Comparative data between them is still evolving, and the choice depends on tumor characteristics and patient preference. Raj Nigam - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-raj-nigam/ Nanoknife - https://www.thefocaltherapyclinic.co.uk/focal-therapy/nanoknife-ire-treatment/ HIFU - https://www.thefocaltherapyclinic.co.uk/focal-therapy/hifu-treatment-prostate-cancer/ 00:00 Using HIFU for Posterior Prostate Tumors 00:13 How NanoKnife Differs from HIFU 00:23 Why NanoKnife Is Used for Anterior Tumors 00:38 Is HIFU or NanoKnife Better? 01:00 Treatment Choice Based on Tumor Location 01:07 Future Research & Refining Treatment Selection

TRANSCRIPT
Mr. Raj Nigam: At present, we are using **HIFU** to treat tumors located in the **posterior part of the prostate**, which is **closest to the rectum**. This is because **HIFU energy is delivered through the rectum**. ### **How NanoKnife Differs** - **NanoKnife uses electrodes** placed through the **perineum** instead of the rectum. - This allows treatment in **any part of the prostate**, guided by **MRI-ultrasound fusion**. - Currently, we are using **NanoKnife for anterior (top) prostate tumors**, where it is **proven to be safe**. ### **Which Treatment is Better?** - We **do not yet have comparative data** showing whether **HIFU or NanoKnife** is superior. - **Treatment choice is based on tumor location**: - **HIFU for posterior tumors**. - **NanoKnife for anterior tumors**. As research continues, we aim to refine our approach and determine the **best treatment for different prostate cancer cases**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Feature HIFU
Treatment Type Minimally invasive focal therapy
Energy Used High-intensity focused ultrasound (thermal)
Hospital Stay Outpatient (same day)
Urinary Incontinence Risk Very low (<1%)
Erectile Dysfunction Risk Low (~5-10%)
Repeatable Treatment? Yes
Best for Tumour Location Tumours near the base of the prostate gland
Suitability Men eligible for focal therapy where tumour location is near the base of the prostate gland
Follow-Up Care Regular PSA testing and occasional MRI scans

Am I Suitable for HIFU Treatment?

Most men with localised prostate cancer (Gleason 3+3 or 3+4, stage T1-T2) are suitable for HIFU treatment, particularly when the tumour is located in the posterior or base region of the prostate. Your suitability is assessed through mpMRI imaging and targeted biopsy, reviewed by your consultant in a multidisciplinary team discussion.

HIFU may be appropriate if your cancer is:

Localised (has not spread outside the prostate)

Intermediate risk (typically Gleason 6 or 7, PSA under 15-20 ng/mL)

Located in the posterior or lateral parts of the prostate

You have a life expectancy of at least 8-10 more years

HIFU is particularly effective for posterior tumours because the ultrasound probe is positioned in the rectum, giving direct access to the back of the prostate. For anterior tumours -- those at the front of the prostate, closer to the abdominal wall -- The Focal Therapy Clinic offers NanoKnife IRE treatment (NICE-approved under IPG768), which can reach areas that HIFU cannot.

Mr Alan Doherty, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3279241), explains: "Not every patient is suitable for focal therapy, and we're transparent about that. We assess every referral carefully with mpMRI and targeted biopsy before recommending treatment."

It could also be the right choice if you are on the NHS Active Surveillance protocol and want to move to active treatment.
Check your suitability

Success rates

In our clinic's experience treating over 2,000 patients, HIFU achieves an 88% success rate at five years -- meaning 88% of men need no further radical treatment. Over 90% of men are cancer-free at the 12-month follow-up. These outcomes are from The Focal Therapy Clinic's own audit data (n=265).

“Longer-term evidence is equally encouraging after 7-8 years of follow-up, failure-free survival rates for focal therapy are equivalent to surgery and radiotherapy — but with dramatically fewer side effects ”

Mr Tim Dudderidge
Consultant Urologist

Cancer control at 5 years:

88% needed no further radical treatment

Sexual function preserved:

90%+

Urinary continence:

97% (n=265)


HIFU is approved by NICE under Interventional Procedures Guidance IPG424, confirming sufficient evidence of safety and efficacy for use in both the NHS and private practice.

In the 5-10% of cases where cancer is not fully treated or recurs, further treatment remains available. Mr Raj Nigam, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3265226), notes: "In the unfortunate 5-10% of cases where the cancer is not fully treated or returns in another part of the prostate, additional options are available. You can undergo another focal therapy session or pursue traditional treatments such as radical prostatectomy or radiotherapy if needed."

This retreatability is a key advantage -- unlike radical prostatectomy, HIFU does not burn bridges.

Mr Marc Laniado: MRI US Fusion technology and focal therapy success rates
01:00
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NanoKnife (IRE) Focal Therapy for Prostate Cancer
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SUMMARY
Mr. Marc Laniado (Consultant Urologist, The Focal Therapy Clinic): MRI fusion improves focal therapy accuracy, ensuring over 90% of men are cancer-free at one year. Globally, 7580% of men avoid radical treatment for 610 years post-focal therapy, making it an effective and minimally invasive option for prostate cancer. Marc Laniado - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-marc-laniado/ MRI US Fusion Technology - https://www.thefocaltherapyclinic.co.uk/focal-therapy/medical-suitability/mri-scans-prostate-cancer/ Success Rates - https://www.thefocaltherapyclinic.co.uk/focal-therapy/success-and-clinical-evidence/ 00:00 Introduction: MRI Fusion in Focal Therapy 00:04 Why MRI Fusion Matters (Precision & Accuracy) 00:14 One-Year Success Rates (Over 90% Cancer-Free) 00:22 Long-Term Success of Focal Therapy (Global Data) 00:34 Avoiding Radical Treatments (610 Years Control) 00:52 Key Takeaway: Precise, Minimally Invasive & Effective

TRANSCRIPT
Mr. Marc Laniado: At **The Focal Therapy Clinic**, we perform **focal therapy using MRI fusion**, which significantly improves **treatment accuracy**. ### **Why MRI Fusion Matters** - We use **real-time MRI guidance** during treatment to **precisely target the cancer**. - This ensures we treat **the cancerous area and a surrounding margin**, reducing the risk of recurrence. - As a result, **our one-year success rates are excellent**—**over 90% of men are cancer-free** based on **MRI and PSA criteria**. ### **Long-Term Success of Focal Therapy** - Looking at global data, **focal therapy (often without MRI fusion) has been shown to delay or avoid radical treatment**. - **75–80% of men remain free from needing surgery or radiotherapy for 6–10 years after treatment**. - This means that **4 out of 5 men successfully avoid radical treatment while maintaining cancer control**. These **strong results** highlight the **effectiveness of MRI-guided focal therapy** in providing **precise, minimally invasive treatment with excellent long-term outcomes**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.

How Does HIFU Compare to Surgery and Radiotherapy?

HIFU focal therapy offers a middle ground between active surveillance and radical whole-gland treatments. Where active surveillance means monitoring without treating, and radical prostatectomy or radiotherapy treats the entire prostate, HIFU targets only the cancerous tissue -- preserving quality of life while actively treating the disease.

Outcome HIFU Focal Therapy (FTC data) Radical Prostatectomy Radiotherapy
Sexual function preserved 90%+ (FTC audit) 30-70% 50-70%
Urinary continence 97% (FTC audit, n=265) 80-95% (at 12 months) 90-95%
Cancer control at 5 years 88% (FTC audit) 90-95% 85-90%
Procedure time 1-2 hours 3-4 hours 20-37 sessions over weeks
Hospital stay Day case (home same day) 1-3 nights Outpatient
Recovery to normal activity 85% back to work within 2 weeks 4-6 weeks 2-4 weeks
Retreatment possible Yes No (prostate removed) Limited
NICE status Approved (IPG424) Standard care Standard care

Source: FTC one-year outcome audit (n=265) and published peer-reviewed literature. Radical prostatectomy and radiotherapy figures represent ranges from meta-analyses.

This comparison helps you understand the differences -- the right choice depends on your cancer's grade, stage, and location, as well as your personal priorities. Your consultant will discuss which options are most appropriate for your individual case.

Note: The existing "Choosing Between NanoKnife & HIFU: Key Factors" comparison table (currently further down the page) should be KEPT as-is. This new table compares HIFU to non-focal treatments. The existing table compares HIFU to NanoKnife.



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What to Expect: The HIFU Procedure Step by Step

  • Pre-treatment imaging (MRI/ultrasound) to pinpoint the cancer
  • Blood tests (PSA levels, general health)
  • Discussion of anesthesia options (general or spinal)
  • Bowel preparation (as advised by your medical team)
      • Mr Tim Dudderidge: How should I prepare for focal therapy
      00:25
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      Care: Before Treatment
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      SUMMARY
      Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Before focal therapy, youll receive fasting instructions and arrival details. Avoid a heavy meal the night before, and if you have any questions, check with the ward nurses to ensure youre fully prepared for your procedure. Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ Focal Therapy Process - https://www.thefocaltherapyclinic.co.uk/focal-therapy/ Care Pathway - https://www.thefocaltherapyclinic.co.uk/process/

      TRANSCRIPT
      Mr. Tim Dudderidge: Before your **focal therapy procedure**, you will receive **specific fasting instructions** and **your hospital arrival time** from the booking team. ### **Pre-Treatment Preparation** - Follow the **fasting instructions** provided. - If you're **unsure about any details**, check with **ward nurses in advance**. - Avoid eating a **heavy meal the night before** your procedure. - Pack a **small bag with essentials** for your hospital visit. Aside from these simple steps, **there is very little preparation required** for focal therapy.

      This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: What happens on the day of a focal therapy treatment?
01:37
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Care: On the Day
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Focal therapy is a day-case procedure performed under general anesthesia, typically lasting 6090 minutes. A catheter is required for 57 days, and most patients resume normal activities soon after, making it a minimally invasive and efficient treatment option. 00:00 Introduction Mr. Tim Dudderidge introduces what to expect on the day of focal therapy. 00:01 Arrival & Preparation Arrive starved for anesthesia, nursing checks, and enema for ultrasound clarity. 00:21 Procedure Details Transferred to theater, anesthetized, procedure lasts 6090 minutes. 00:32 Post-Procedure Recovery Wake in recovery, food & drink provided, catheter management explained. 00:53 Going Home & Recovery Must be driven home, catheter stays 57 days, most men return to normal life soon after removal. 01:38 Key Takeaway Focal therapy is a straightforward day-case procedure with quick recovery. Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ Focal therapy timeline - https://www.thefocaltherapyclinic.co.uk/focal-therapy/

TRANSCRIPT
Mr. Tim Dudderidge: ### **On the Day of Your Focal Therapy Procedure** 1. **Arrival & Pre-Procedure Preparation** - You will **arrive at the hospital starved**, ready for **general anesthesia**. - Nursing staff will **greet you and perform necessary checks**. - An **enema will be administered** to clear the bowels, ensuring a **clear ultrasound view** during treatment. 2. **Procedure Details** - You will be **transferred to the operating theater**, where final checks are completed. - Once the **anesthetist is happy**, you will be placed under **general anesthesia**. - The **procedure lasts 60–90 minutes**, during which the targeted prostate area is treated. 3. **Post-Procedure Recovery** - After the procedure, you will **wake up in the recovery room**, spending about **30 minutes there** before returning to the ward. - You will be given **food and drink** once fully awake. - A **catheter** will be attached to your leg, and **nurses will show you how to manage it**. 4. **Going Home & Recovery** - Once you have **fully recovered from anesthesia**, you can go home, but **someone must drive you** as you **cannot drive for 36 hours**. - **Normal activities can resume**, but the **catheter will stay in for 5–7 days**. - After **catheter removal**, most men can **return to normal life with minimal restrictions**. ### **Key Takeaway** Focal therapy is a **straightforward day-case procedure**, and **recovery is quick**, allowing patients to **resume daily life within a week**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: Do I need a general anaesthetic for focal therapy
00:46
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Care: On the Day
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): **Most patients can safely undergo general anesthesia for HIFU, NanoKnife, and cryotherapy**. **Spinal anesthesia is not suitable for HIFU or NanoKnife but may be an option for cryotherapy**. Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ Care Pathway - https://www.thefocaltherapyclinic.co.uk/process/ Focal Therapy - https://www.thefocaltherapyclinic.co.uk/focal-therapy/

TRANSCRIPT
Mr. Tim Dudderidge: Nearly all patients can safely undergo the **general anesthesia required for a HIFU procedure**. ### **Anesthesia for Focal Therapy Treatments** - **HIFU (High-Intensity Focused Ultrasound)** - Requires **general anesthesia**. - **Spinal or regional anesthesia is not suitable**, as past attempts have not worked well. - This was learned from **early experiences**, and general anesthesia is now the standard. - **Cryotherapy** - Can potentially be performed under **spinal anesthesia**, but general anesthesia is preferred. - **NanoKnife (Irreversible Electroporation)** - Requires **general anesthesia** due to **muscle effects during the procedure**. For patients considering **focal therapy**, general anesthesia is **safe and well-tolerated in nearly all cases**, ensuring **optimal treatment conditions**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: What happens during focal therapy
01:38
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Care: On the Day
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Focal therapy procedures last 6090 minutes under anesthesia, using MRI-ultrasound fusion to precisely target cancer. HIFU, cryotherapy, and NanoKnife effectively destroy cancer cells while preserving healthy tissue, offering a minimally invasive alternative to surgery or radiotherapy. Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ Focal Therapy - https://www.thefocaltherapyclinic.co.uk/focal-therapy/ 00:00 Focal Therapy Procedure Overview (Anesthesia & Positioning) 00:07 Imaging & Treatment Planning (MRIUltrasound Fusion) 00:40 HIFU Treatment Explained (Heat-Based Therapy) 00:59 Cryotherapy & NanoKnife (Needle-Based Therapies) 01:25 Procedure Duration & Recovery (6090 Minutes, Catheter Placement) 01:30 Key Benefit: Precision with Functional Preservation

TRANSCRIPT
Mr. Tim Dudderidge: During a **typical focal therapy procedure**, you will be **asleep under general anesthesia**, with your legs positioned in **lithotomy** to allow access to the **perineum**. ### **Imaging & Treatment Planning** - A **transrectal ultrasound probe** is placed in the rectum. - In **HIFU**, this is the **treatment probe**; in **cryotherapy and electroporation (NanoKnife)**, it is a **standard ultrasound probe**. - The **ultrasound images are linked to your MRI scan** to identify the lesion and ensure **precise targeting**. - The treatment is planned with a **margin around the lesion**, capturing all cancer cells, including any microscopic “tentacles” of disease. ### **Treatment Procedures** 1. **HIFU (High-Intensity Focused Ultrasound)** - Uses **overlapping treatment zones**, typically **three or four sessions**, where heat destroys the cancer cells. - A **urethral catheter** is placed at the end of the procedure. 2. **Cryotherapy & NanoKnife (Electroporation)** - Involve placing **needles into the prostate** at various locations. - **Cryotherapy freezes cancer cells**, while **NanoKnife uses electrical pulses** to destroy tissue. - **MRI-ultrasound fusion** ensures accurate targeting and a sufficient **treatment margin**. ### **Procedure Duration & Recovery** - The treatment typically lasts **60–90 minutes**. - A **catheter is placed at the end of the procedure** to aid recovery. Focal therapy is **highly precise**, ensuring **effective cancer control** while preserving **urinary and sexual function** as much as possible.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: Recovery after focal therapy
01:04
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Care: Recovery
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Pain after focal therapy is uncommon, but bladder spasms are the most frequent discomfort, typically lasting 2448 hours. Antispasmodic drugs and simple painkillers help manage symptoms, ensuring a smoother recovery. Mr Alan Doherty - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-alan-doherty/ recovery from Focal Therapy - https://www.thefocaltherapyclinic.co.uk/why-choose-focal-therapy/recovery/ patient stories - https://www.thefocaltherapyclinic.co.uk/about-us/prostate-cancer-stories/ care pathway - https://www.thefocaltherapyclinic.co.uk/process/ 00:00 Introduction: Recovery After Focal Therapy 00:01 Pain Is Not Typically a Major Symptom 00:04 Most Common Side Effect: Bladder Spasms 00:08 Description: Urge to Urinate Despite Proper Drainage 00:20 Duration: Usually Temporary (2448 Hours) 00:27 Management with Antispasmodic Drugs (e.g., Buscopan) 00:38 Other Options: Targeted Bladder Medications (e.g., Solifenacin) 00:43 Managing Pain & Recovery 00:50 Mild Pain from Perineal Bruising 00:52 Relief with Simple Painkillers (Paracetamol, Ibuprofen)

TRANSCRIPT
Mr. Tim Dudderidge: After a **focal therapy procedure**, **pain is not typically a major symptom**. ### **Most Common Side Effect: Bladder Spasms** - The most frequent discomfort is **bladder spasms**—a **strong urge to urinate** even though the **catheter is draining properly**. - This symptom is usually **temporary**, lasting **24–48 hours**. - It can be managed with: - **Antispasmodic drugs** like **Buscopan (hyoscine butylbromide)**. - **More targeted bladder medications**, such as **Solifenacin**. ### **Managing Pain & Recovery** - **Pain is usually mild** and related to **bruising in the perineum**. - **Paracetamol and ibuprofen*

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge How long does it take to recover from focal therapy
01:25
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Care: Recovery
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Recovery after focal therapy is quick. Most patients resume light activities within a week and return to normal physical activity soon after. Some may experience temporary urgency or fatigue, but side effects are typically mild compared to traditional treatments.

TRANSCRIPT
Mr Tim Dudderidge: After focal therapy, you can drive again after 48 hours as long as the catheter is not causing significant discomfort. However, if the catheter is bothersome or distracting, it is best to wait until it has been removed before driving. During the first week after treatment, you can engage in most light activities, and we encourage plenty of walking to stay active. Once the catheter is removed, patients can typically return to normal physical activities, including sports. I have had patients go skiing soon after catheter removal, and one even sent me a video of himself playing ice hockey just 10 days after treatment. Regarding work, recovery varies depending on your job. Many office-based workers are able to work on their laptops while still in the hospital. If you are self-employed, you may find it easy to return to work quickly. However, if your job is physically demanding, you might need a couple of weeks to adjust, as bladder behavior can be slightly more frequent or urgent at first. Beyond that, recovery is generally very quick. Some people experience mild fatigue after treatment, which can be surprising. It is important to listen to your body and gradually return to normal activity at a comfortable pace.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge Will I need to wear a pad after focal therapy
00:32
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Care: Recovery
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Post-surgery pad use is usually due to sphincter damage, leading to long-term incontinence risks. In contrast, focal therapy may cause only temporary urgency-related leakage, with most patients regaining full bladder control quickly. Website: https://www.thefocaltherapyclinic.co.uk LinkedIn: linkedin.com/company/the-focal-therapy-clinic/ Facebook: facebook.com/TheFocalTC Telephone: +44 (0) 207 036 8870 #FocalTherapy #ProstateHealth #MinimallyInvasive #MensHealth #ProstateCancerTreatment #Urology

TRANSCRIPT
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Typically, the reason men have to wear pads after surgery is due to sphincter damage, which can take a long time to heal. Occasionally, men may experience some frequency and urgency after focal therapy treatments, where an overactive bladder can lead to leakage just before reaching the toilet. For these men, wearing a pad is a temporary issue and usually short-lived.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Tim Dudderidge: When can I go home after focal therapy
00:40
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Care: After your treatment
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SUMMARY
Mr. Tim Dudderidge (Consultant Urologist, The Focal Therapy Clinic): Most patients go home within a few hours after focal therapy, once theyve eaten, had fluids, and been shown how to use the catheter. Those traveling far may choose to stay in a nearby hotel overnight for added convenience and comfort. Mr Tim Dudderidge - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-tim-dudderidge/ Recovery after Focal Therapy - https://www.thefocaltherapyclinic.co.uk/why-choose-focal-therapy/recovery/ Book your consultation - https://www.thefocaltherapyclinic.co.uk/contact/ 00:00 Introduction: Pain After Focal Therapy 00:04 Common Side Effect: Bladder Spasms 00:08 What Bladder Spasms Feel Like (Urgency Despite Catheter Drainage) 00:20 Duration of Symptoms: Usually 2448 Hours 00:27 Managing Discomfort: Antispasmodic Medications (Buscopan) 00:38 Targeted Bladder Medications (Solifenacin) 00:43 Pain Management & Recovery Tips 00:50 Mild Pain or Bruising: Paracetamol and Ibuprofen Recommended Website: https://www.thefocaltherapyclinic.co.uk LinkedIn: linkedin.com/company/the-focal-therapy-clinic/ Facebook: facebook.com/TheFocalTC Telephone: +44 (0) 207 036 8870 #FocalTherapy #ProstateCancer #MensHealth #MinimallyInvasive #CancerRecovery #ProstateHealth

TRANSCRIPT
Mr. Tim Dudderidge: Most patients **go home within a few hours** of returning to the ward after **focal therapy**. ### **What to Expect Before Discharge** - You’ll have time to **eat and drink**. - You’ll be **shown how to use the catheter**. - We’ll ensure you **don’t feel too groggy** before leaving. ### **Evening Procedures & Travel Considerations** - We often schedule procedures for the **late afternoon (Twilight list at 6:00 PM)**. - Even if treated late, **most patients can still go home that evening**, often around **9:00 PM**. - **For those traveling a long distance**, we may recommend **staying overnight in a local hotel** and traveling home the next morning. Most men **recover comfortably at home**, with clear instructions on **aftercare and follow-up**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Marc Laniado: Will I need help getting or maintaining an erection after focal therapy?
00:41
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Care: After your treatment
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SUMMARY
Mr. Marc Laniado (Consultant Urologist, The Focal Therapy Clinic): Most men regain normal erections within a few months after focal therapy, though medications can help. By one year, function is usually restored, with rare cases needing further treatment or additional support. Mr Marc Laniado - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-marc-laniado/ sex and relationships - https://www.thefocaltherapyclinic.co.uk/why-choose-focal-therapy/sex-and-relationships/ prostate cancer and ejaculation - https://www.thefocaltherapyclinic.co.uk/blog/does-prostate-cancer-stop-you-from-ejaculating/

TRANSCRIPT
Mr. Marc Laniado: If you had **completely normal erections** before treatment, most men find that their **erections return within a few months** after focal therapy. ### **How to Support Recovery** I usually recommend taking a **low-dose erectile function medication. This helps: - **Boost blood flow to the nerves and penis**. - **Improve recovery and support erectile function return**. ### **What to Expect Over Time** - By **one year**, most men find their erections are **normal or close to normal**. - **Some men may need to continue taking medication** for erections even if they didn’t before. - **Very rarely**, men require additional treatments such as **injections or other interventions**, but this is uncommon. With **proper support and time**, **most men regain their sexual function after focal therapy**, maintaining a **high quality of life**.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Mr Raj Nigam After focal therapy what tests are done to see if it was effective
01:38
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Care: After your treatment
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SUMMARY
Mr. Raj Nigam (Consultant Urologist, The Focal Therapy Clinic): We closely monitor all focal therapy patients with regular PSA tests and MRI scans to track treatment success. If recurrence occurs (510%), further focal therapy or traditional treatments like surgery or radiotherapy remain viable options, ensuring flexible and effective cancer management.

TRANSCRIPT
Mr Raj Nigam: We carefully follow up with all our focal therapy patients. It is essential that after your treatment, you have access to us for ongoing monitoring. We track your progress in two ways. First, we conduct PSA blood tests every three months for the first year. Even if your PSA levels drop significantly and you feel completely fine, we always perform an MRI scan at the end of the first year. This ensures that the treated area has disappeared and that no new abnormalities have developed in the remaining prostate tissue. If everything looks good, we transition to six-monthly PSA tests for the next two years, followed by annual PSA checks. Many men also opt for another MRI scan at three or five years, which is entirely possible, though we primarily rely on PSA levels to guide further imaging needs. In the unfortunate 5–10% of cases where the cancer is not fully treated or returns in another part of the prostate, additional options are available. You can undergo another focal therapy session or pursue traditional treatments such as radical prostatectomy or radiotherapy if needed.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.

What Are the Side Effects of HIFU?

The most common side effects after HIFU are temporary and resolve within days to weeks. In our audit of 265 patients at The Focal Therapy Clinic, less than 2% experienced urinary incontinence, and over 90% maintained their sexual function. By treating only the cancerous tissue, HIFU avoids the widespread damage to nerves and muscles that causes side effects in whole-gland treatments.

Symptom Frequency Duration
Temporary urinary catheter Standard (all patients) Typically 1-3 days
Increased urinary frequency or urgency Common 1-4 weeks
Mild perineal discomfort Common 2-3 days
Light blood in urine Common in first few days 1-3 days
Change in erectile function 5-10% experience some change; 90%+ maintain function (FTC audit) Usually temporary (most recover within months)
Urinary tract infection Uncommon (<5%) Treated with antibiotics
Urinary incontinence Rare (<2%, FTC audit) -
Retreatment required 10-20% within 5 years -


Recovery After HIFU Treatment

Most men go home the same day as their HIFU procedure and return to normal activities within one to two weeks. Our patient data shows 85% of men return to work within two weeks of focal therapy at The Focal Therapy Clinic. There is no surgical wound, no stitches, and no prolonged bed rest.

Your recovery timeline:

  • Day of treatment: Home the same evening in most cases
  • Days 1-3: Rest at home. Temporary catheter in place. Mild discomfort managed with paracetamol and ibuprofen
  • Days 5-7: Catheter removed (at GP surgery or by district nurse)
  • Weeks 1-2: Gradual return to normal activities including work
  • Week 6: Follow-up appointment with your consultant
  • Month 3: First PSA blood test
  • Month 12: Follow-up MRI scan to confirm treatment success


How Much Does HIFU Treatment Cost?

HIFU treatment at The Focal Therapy Clinic costs from [CONFIRM EXACT PRICE WITH CLINIC]. This is an all-inclusive fee covering your consultant's time, anaesthetist, the procedure, day-case facility, and all standard follow-up appointments including PSA testing and MRI.

What is included:

  • Pre-operative assessment and MRI review
  • Consultant urological surgeon performing the procedure
  • General anaesthetic and anaesthetist fees
  • Day-case facility and nursing care
  • Post-operative catheter supplies
  • Follow-up consultations at 6 weeks, 3, 6, and 12 months
  • PSA blood tests and 12-month follow-up MRI

Insurance: HIFU is recognised by major UK private medical insurers including Bupa, AXA Health, Aviva, and Vitality.

View our full fee schedule

Questions to Ask Your Doctor About HIFU

Am I a good candidate for HIFU prostate cancer treatment?

Are You a Good Candidate for HIFU (High-Intensity Focused Ultrasound)?

  • Your cancer is intermediate risk (usually Gleason 3+4 or 4+3).
  • The cancer is localised (hasn’t spread outside the prostate).
  • Your PSA is under 15–20 ng/mL.
  • You are expected to live at least 8–10 more years.
  • The cancer is in one main spot and small enough to target.

Note: HIFU is not usually used for very low-risk or very high-risk cancer. It aims to treat the cancer while keeping side effects like incontinence or erection problems low.

"I had the HIFU procedure with Tim Dudderidge and was very happy with the results... I have absolutely no incontinence and I'm fully sexually active without any side effects."

– Graham Pipe, HIFU patient

“Focal HIFU treats cancer with lower side effects.”

– Mr. Tim Dudderidge, Consultant Urological Surgeon (FRCS(Urol), GMC: 4505451)

Is HIFU available at your clinic, and how experienced is the team?

HIFU is available at the Focal Therapy Clinic in the UK. It is one of the leading centres for focal therapy, including HIFU, NanoKnife, and Cryotherapy. The team includes top urologists like Mr Tim Dudderidge (GMC: 4505451), Mr Marc Laniado (GMC: 3343931), Mr Raj Nigam (GMC: 3265226) and Mr Alan Doherty (GMC: 3279241) who have treated over 2,000 patients successfully.

Patient quote: "The team at The Focal Therapy Clinic made me feel very reassured. From the first consultation through to my HIFU treatment and follow-up, everything was explained clearly." — Perry Letcher, FTC HIFU patient
How does HIFU compare to other treatments like NanoKnife, surgery or radiotherapy?

HIFU targets only the cancerous area, not the whole prostate. This means significantly fewer side effects compared to surgery or radiotherapy. In our clinic's audit of 265 patients, 90%+ maintained sexual function and 97% maintained urinary continence after focal HIFU. NanoKnife IRE is also precise and may be preferred for anterior tumours that HIFU cannot reach.

"I have absolutely no incontinence and I'm fully sexually active without any side effects." — Graham Pipe, HIFU patient

"Focal HIFU treats cancer with minimal side effects. It preserves sexual function reliably." — Mr Alan Doherty, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3279241)

How many times can HIFU be repeated if cancer comes back?

HIFU can be safely repeated if the cancer comes back in the treated area. Studies show about 15 to 20% of men may need a second round, and it usually works well. Follow-up scans and biopsies help decide if another treatment is needed.

Urologist quote: “Focal HIFU lets us hit the cancer without harming the rest of the prostate.” – Mr Raj Nigam, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3265226)
What are the success rate and potential side effects for my specific case?

For men with intermediate-risk, localised prostate cancer, HIFU has a success rate of approximately 88% at five years (Ganzer et al., 2017) — meaning no need for surgery, radiation, or further treatment. Side effects are typically mild: less than 2% experience urinary incontinence, and 90%+ maintain sexual function (FTC audit, n=265), especially if function was good before treatment.

Urologist quote: “HIFU preserves sexual function reliably.” - Mr Alan Doherty, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3279241)
Patient quote: “I have no incontinence and full sexual function after HIFU.” - Nigel Harris, FTC patient
What follow-up schedule should I expect?
After HIFU, follow-up usually includes:
  • PSA tests every 3 months for the first year
  • MRI scan at 12 months
  • Biopsy only if the MRI scan indicates an area of concern
  • Regular checks for urinary or sexual function

This helps catch any signs of cancer coming back early.

Urologist quote: “Monitoring side effects and recurrence rates is a key part of our research” - Mr Marc Laniado, Consultant Urological Surgeon (FRCS(Urol), FEBU, GMC: 3343931)

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    Choosing Between NanoKnife & HIFU: Key Factors

    Both NanoKnife IRE and HIFU are focal therapy options that treat localised prostate cancer while preserving quality of life. The choice between them depends on tumour location, treatment goals, and patient preferences.
    Benefit NanoKnife Hifu
    Best for Tumour Location Irregularly shaped or near critical structures (nerves, urethra) Well-defined tumours in specific prostate zones
    Preservation of Nerves No heat damage; excellent for preserving erectile function Low risk, but heat may affect nearby structures
    Suitability for Recurrent Cancer Ideal for post-radiation recurrence For tumours near the base of the prostate
    Side Effects Minimal impact on urinary function and sexual health Low risk of incontinence and erectile dysfunction
    Treatment risk Risk of rectal injury at base of prostate Risk of under treatment at front of prostate​

    The Role of MR-US Fusion Technology in Treatment Accuracy

    MRI-Ultrasound (MR-US) Fusion Technology combines high-resolution MRI imaging with real-time ultrasound guidance, allowing for precise targeting of cancerous tissue.

    Benefits of MR-US Fusion Technology

    • Improved Tumour Detection - More accurate than ultrasound alone
    • Greater Targeting Precision - Helps specialists precisely pinpoint tumours
    • Reduces Risk of Missing Cancerous Tissue - Ensures comprehensive tumour destruction

    Mr Marc Laniado: MRI US Fusion technology and focal therapy success rates
    01:00
    Playlist
    NanoKnife (IRE) Focal Therapy for Prostate Cancer
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    SUMMARY
    Mr. Marc Laniado (Consultant Urologist, The Focal Therapy Clinic): MRI fusion improves focal therapy accuracy, ensuring over 90% of men are cancer-free at one year. Globally, 7580% of men avoid radical treatment for 610 years post-focal therapy, making it an effective and minimally invasive option for prostate cancer. Marc Laniado - https://www.thefocaltherapyclinic.co.uk/about-us/our-consultants/mr-marc-laniado/ MRI US Fusion Technology - https://www.thefocaltherapyclinic.co.uk/focal-therapy/medical-suitability/mri-scans-prostate-cancer/ Success Rates - https://www.thefocaltherapyclinic.co.uk/focal-therapy/success-and-clinical-evidence/ 00:00 Introduction: MRI Fusion in Focal Therapy 00:04 Why MRI Fusion Matters (Precision & Accuracy) 00:14 One-Year Success Rates (Over 90% Cancer-Free) 00:22 Long-Term Success of Focal Therapy (Global Data) 00:34 Avoiding Radical Treatments (610 Years Control) 00:52 Key Takeaway: Precise, Minimally Invasive & Effective

    TRANSCRIPT
    Mr. Marc Laniado: At **The Focal Therapy Clinic**, we perform **focal therapy using MRI fusion**, which significantly improves **treatment accuracy**. ### **Why MRI Fusion Matters** - We use **real-time MRI guidance** during treatment to **precisely target the cancer**. - This ensures we treat **the cancerous area and a surrounding margin**, reducing the risk of recurrence. - As a result, **our one-year success rates are excellent**—**over 90% of men are cancer-free** based on **MRI and PSA criteria**. ### **Long-Term Success of Focal Therapy** - Looking at global data, **focal therapy (often without MRI fusion) has been shown to delay or avoid radical treatment**. - **75–80% of men remain free from needing surgery or radiotherapy for 6–10 years after treatment**. - This means that **4 out of 5 men successfully avoid radical treatment while maintaining cancer control**. These **strong results** highlight the **effectiveness of MRI-guided focal therapy** in providing **precise, minimally invasive treatment with excellent long-term outcomes**.

    This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.

    A consultation with a prostate cancer specialist is necessary to determine the best treatment choice.
    Book your consultation

    Frequently Asked Questions About HIFU

    What exactly is HIFU, and how does it treat prostate cancer?
    HIFU (High-Intensity Focused Ultrasound) uses thermal ultrasound waves delivered via a rectal probe to rapidly heat and destroy targeted cancer cells. This non-invasive procedure is guided by MRI-ultrasound fusion technology and performed under anaesthesia as outpatient care. The treated cells are naturally eliminated by the body over time.
    What are the functional outcomes of HIFU compared to radical surgery?
    HIFU offers similar cancer control for appropriate candidates with significantly fewer side effects. Urinary incontinence affects less than 2% with HIFU (FTC audit, n=265) versus 5–20% after surgery. Sexual function is preserved in over 90% with HIFU (FTC audit, n=265). Recovery is typically measured in days, not weeks.
    What are the overall success rates for HIFU focal therapy in localised cancer?
    Five-year data shows highly positive long-term outcomes for localised intermediate-risk disease. Approximately 88% of men avoid any further radical treatment at 5 years, and over 90% are cancer-free at the 1-year follow-up.
    Who is the ideal patient best suited for HIFU treatment?
    HIFU is best suited for men with localised intermediate-risk cancer (e.g., Gleason 6 or 7, PSA <15–20 ng/mL). Anatomically, it works optimally for lesions located in the posterior or base of the prostate, which are easily targeted via the rectal probe.
    What are HIFU's limitations, particularly compared to NanoKnife IRE?
    The primary limitation is the effective range of the thermal ultrasound waves (limited to about 3.0 cm from the rectal probe), posing a risk of undertreatment for anterior prostate tumours. Calcifications can also block HIFU, making NanoKnife safer in such cases.
    What side effects and recovery steps are involved after the procedure?
    Recovery is rapid, but a urinary catheter is typically required for 3–7 days. Temporary urinary frequency, urgency, and mild perineal discomfort are common for a few days. Severe complications are uncommon.
    Can HIFU treatment be safely repeated if the cancer recurs?
    Yes, HIFU can be safely repeated if cancer recurs. Approximately 15–20% of men require a second session. Regular monitoring via PSA and MRI ensures early detection, preserving the option for retreatment.
    Book your consultation

    HIFU treatment consultation at The Focal Therapy Clinic

    "HIFU for prostate cancer has been the subject of clinical research since the late 1990s, with UK university hospitals playing a leading role in clinical trials that established its safety and efficacy for focal treatment. "


    Reference List

    Ahmed HU et al. (2015). Focal therapy for localised prostate cancer: a systematic review of the literature. Nature Reviews Urology.

    Ganzer R, Fritsche HM, Brandtner A, et al. (2017). Five-year outcome of HIFU treatment for localised prostate cancer. Urologia Internationalis.

    The Focal Therapy Clinic – Prostate Cancer Treatments (Internal Resource).

    NHS Resources on Prostate Cancer (Internal/External Resource).

    p>NICE Interventional Procedures Guidance IPG424 (2012). High-intensity focused ultrasound for prostate cancer.

    NICE Health Technology Guidance HTG667 (2024). Sonablate for treating prostate cancer with high-intensity focused ultrasound.

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